Which base always pairs with guanine?

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Study for the Genetics and Molecular Biology Exam. Study using flashcards and multiple choice questions, each question comes with hints and explanations. Get ready for your exam!

Multiple Choice

Which base always pairs with guanine?

Explanation:
Base-pairing specificity in DNA means guanine always pairs with cytosine. They form three hydrogen bonds, which provides extra stability and fits the regular width of the double helix. Adenine pairs with thymine (or uracil in RNA) via two hydrogen bonds, not with guanine, so guanine’s partner is cytosine. This G–C pairing keeps the two strands complementary and helps maintain DNA’s structure.

Base-pairing specificity in DNA means guanine always pairs with cytosine. They form three hydrogen bonds, which provides extra stability and fits the regular width of the double helix. Adenine pairs with thymine (or uracil in RNA) via two hydrogen bonds, not with guanine, so guanine’s partner is cytosine. This G–C pairing keeps the two strands complementary and helps maintain DNA’s structure.

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